Tell us about a time when you had to make a difficult decision during a research study and explain your thought process behind it.

Sample answer to the question

During my research study on viral infections, I encountered a difficult decision regarding the inclusion of a high-risk population in my study. My thought process involved weighing the potential benefits of including this population in terms of a more comprehensive understanding of the virus and its transmission dynamics against the ethical considerations and potential harm to the participants. Ultimately, I decided to consult with the research ethics committee to ensure that the study design and protocols were ethically sound and adequately protected the participants' rights and well-being.

A more solid answer

During my research study on viral infections, I faced a difficult decision related to the selection of appropriate molecular biology techniques and virological methods. The challenge was to choose the most accurate and efficient methods for detecting viral genetic material in patient samples. To tackle this, I thoroughly reviewed the literature, consulted with experts in the field, and conducted preliminary experiments to compare different techniques. Based on the results, I made an informed decision to utilize a combination of RT-PCR and next-generation sequencing to ensure comprehensive analysis of viral genomes. This decision was crucial in obtaining accurate data for further analysis and drawing meaningful conclusions from the study.

Why this is a more solid answer:

The solid answer provides specific details about the candidate's expertise in molecular biology techniques and virological methods. It also demonstrates their critical thinking and problem-solving skills by explaining their thorough research, consultation with experts, and the use of preliminary experiments to make an informed decision. Additionally, it showcases their ability to design and conduct complex research studies by incorporating advanced techniques for accurate data analysis.

An exceptional answer

During my research study on viral infections, I faced a difficult decision regarding the allocation of limited resources for the study. The challenge was to decide between investing in more advanced laboratory equipment or hiring additional research personnel. To address this, I conducted a detailed cost-benefit analysis and consulted with the research team to identify the critical factors influencing the research outcome. After careful consideration, I decided to prioritize hiring additional research personnel to ensure the timely completion of the study and maximize data generation. This decision proved to be effective as the increased manpower allowed us to collect a larger sample size and accelerate the analysis process, leading to more robust findings and faster progress in our research.

Why this is an exceptional answer:

The exceptional answer goes beyond the solid answer by introducing the candidate's ability to manage limited resources and make strategic decisions. It demonstrates their critical thinking and problem-solving skills by conducting a detailed cost-benefit analysis and consulting with the research team. The decision to prioritize hiring additional research personnel aligns with their strong leadership skills and ensures the timely completion of the study. This answer further highlights the candidate's expertise in designing and conducting complex research studies by considering the impact of manpower on data generation and research progress.

How to prepare for this question

Familiarize yourself with a wide range of molecular biology techniques and virological methods commonly used in research studies.
Stay updated with the latest advancements in virology and viral research to enhance your understanding of current methodologies and approaches.
Develop strong critical thinking and problem-solving skills by actively engaging in scientific discussions and tackling challenging research problems.
Practice conducting cost-benefit analyses and making strategic decisions within resource-constrained environments.
Highlight your ability to design and oversee complex research studies during interviews by providing specific examples of study designs and protocols you have developed.

What interviewers are evaluating

Expertise in molecular biology techniques and virological methods
Critical thinking and problem-solving skills
Ability to design and conduct complex research studies